View ivabradine information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and monitoring requirements. Ivabradine is approved to reduce hospitalizations for patients with symptomatic heart failure, reduced ejection fraction, and persistently elevated heart rate despite otherwise maximal medical therapy. However, the eligible patient population is a small fraction of those with heart failure overall. Ivabradine is commonly used to treat certain people with heart failure. Ivabradine may also be used for other conditions as determined by your healthcare provider. How does ivabradine work. Although not approved for other indications, ivabradine has also shown promise in the management of inappropriate sinus tachycardia. Here, the authors review the mechanism of action of ivabradine and salient studies that have led to its current clinical indications and use. What is ivabradine? Ivabradine works by affecting your heart's electrical activity in order to slow the heart rate. Ivabradine is used in adults with chronic heart failure, to help lower the risk of needing to be hospitalized when symptoms get worse. Ivabradine reference guide for safe and effective use from the American Society of Health-System Pharmacists (AHFS DI). Ivabradine, sold under the brand name Procoralan among others, is a medication, which is a pacemaker current (I f) inhibitor, used for the symptomatic management of heart-related chest pain and heart failure. Corlanor (ivabradine) is a medication that's taken by mouth to treat certain types of heart failure in adults and children ages 6 months and older. Doses are typically taken twice a day with food. It is also used to treat heart failure in children 6 months of age and older who have stable heart failure, with symptoms, caused by an enlarged heart (dilated cardiomyopathy). This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Ivabradine is used to treat certain adults with heart failure (condition in which the heart is unable to pump enough blood to the other parts of the body) to decrease the risk that their condition will worsen and need to be treated in a hospital.